The Mechanism of MicroRNAs Network in Alzheimer's Disease

Shanghai Mental Health Center1,000 enrolled

Overview

MicroRNAs network, such as MicRNA107 et al, regulate the pathology of Alzheimer's disease and the clinical validation in diagnosis AD.

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Alzheimer Disease

Interventions

MicRNAs testDIAGNOSTIC_TEST

plasma micRNAs concentration

Eligibility

Sex: ALLMin age: 60 YearsMax age: 90 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * NIA-AA MCI due to AD clinical criteria for MCI due to AD * NIA-AA AD clinical criteria for AD Exclusion Criteria: * Other type of dementia

Locations (1)

Department of Psychogeriatrics，Shanghai Mental Health Center

Shanghai, Shanghai Municipality, China

Outcomes

Primary Outcomes

MicRNAs diagnosis validation for aMCI

MicRNAs concentration in plasma among three groups

Time frame: 5 years

Data from ClinicalTrials.gov

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