A bacterial infection of an artificial joint is a serious complication that often requires additional surgery to exchange the arthroplasty. It is also difficult to recognize an infected joint, as the symptoms caused by the infection are very similar to those of other problems with arthroplasties, such as loosening of the implant. To improve the ability to diagnose prosthetic joint infections, this study compares the levels of calprotectin, a specific inflammatory protein, in the joint fluid of infected joints and joints with other complications. The underlying hypothesis is that the level of calprotectin in infected joints is significantly higher, thus facilitating the diagnosis of prosthetic joint infection.
Study Type
OBSERVATIONAL
Enrollment
500
Semiquantitative point of care photometric assay for the calprotectin level in joint fluid aspirate
Department of Orthopedics and Sports Orthopedics, Klinikum rechts der Isar, Technical University Munich
Munich, Bavaria, Germany
RECRUITINGDiagnostic accuracy of synovial fluid calprotectin
The level of synovial fluid calprotectin measured in joint fluid aspirate as a diagnostic test for prosthetic joint infection. The accuracy is calculated by comparing its results with the International Consensus Meeting (ICM) on prosthetic joint infection criteria of 2018.
Time frame: Intraoperatively
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.