Retrospective observational cohort study investigating Single modality Trans Oral Robotic surgery for primary oropharyngeal cancer: exploring the impact of surgical Margins on local disease recurrence.
The STORM study will examine transoral surgery performed before 31st July 2019. STORM is a retrospective observational cohort study, involving international centres performing TORS for primary OPSCC. The main aim of this study is to explore the impact of surgical margins on local disease recurrence in primary oropharyngeal squamous cell carci-noma treated with transoral robotic surgery (TORS) without adjuvant therapy. The primary objective is to report local recurrence-free survival. The primary endpoint will be Local recurrence-free survival time. The secondary objectives are to report overall survival, disease-specific survival and disease-free survival, and to report post-operative haemor-rhage rates. The secondary endpoints include Overall survival time, Dis-ease-specific survival time, Disease-free survival time, Post-operative haemorrhage time. Exploratory objective to identify a clinically relevant cut-off for surgical margins as a predictor of local disease recurrence.
Study Type
OBSERVATIONAL
Enrollment
500
The Royal Marsden Hospital
London, United Kingdom
RECRUITINGLocal recurrence-free survival time
Time frame: At 2 years
Overall survival time
Time frame: At 2 and 5 years
Disease-specific survival time
Time frame: At 2 and 5 years
Disease-free survival time
Time frame: At 2 and 5 years
Post-operative haemorrhage time
Time frame: Within 30 days
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