Bupivacaine vs Oxybuprocaine Topical Anesthesia in IVI

Early Phase 1CompletedNCT05069350

Research Institute of Ophthalmology, Egypt100 enrolled

Overview

comparing two local anaesthetic agents, Bupivacaine 0.5% versus Oxybuprocaine used topically to provide surface anaesthesia before IVI procedures.

In preparation zone, we will cannulate the patients, connect them to the pulse oximetry and we will start providing appropriate surface anaesthesia for an adequate period of time before the patient administration of the injection, by applying the anaesthetic agents, 3 times with 5 minutes interval, for 15 minutes and then waitng the injection All patients are informed that they are going to receive topical anaesthetic agent before the IVI. pain is monitored during the injection by using the 11 points verbal numerical pain scaling as zero is for no pain and 10 is for severe unbearable pain.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

TRIPLE

Enrollment

100

Conditions

Pain, Acute

Interventions

bupivacaine 0.5% and oxubuprocaineDRUG

using each drug as surface anesthesia before intravitreal injections

Eligibility

Sex: ALLMin age: 30 YearsMax age: 70 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All patients between 30 to 70 years Exclusion Criteria: * uncooperative patients

Locations (1)

Research Institute of Ophthamology

Giza, Haram, Egypt

Outcomes

Primary Outcomes

verbal pain numerical scaling

11 point scale from 0-10 zero measns No pain 10 means severe unbearable pain

Time frame: 10 minutes

Data from ClinicalTrials.gov

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