Role of Oral Steroids in Reducing Recurrence of Urethral Stricture After Direct Vision Internal Urethrotomy

Services Hospital, Lahore180 enrolled

Overview

It was a randomized controlled trial conducted at department of Urology, Armed Forces Institute of Urology, Rawalpindi from 1st January, 2018 July 2019 to 31st March 2021 to determine the role of oral steroids after Direct Vision Internal Urethrotomy to reduce the recurrence rate of urethral strictures.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

180

Conditions

Recurrence

Interventions

Steroid DrugDRUG

In this group Oral steroid medication after Direct Vision Internal Urethrotomy

No steroidDRUG

In this group no Oral steroid medication (palcebo medication) after Direct Vision Internal Urethrotomy

Eligibility

Sex: MALEMin age: 20 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients with urethral stricture with restricted urine flow of \< 15 ml/min on uroflowmetry Exclusion Criteria: * Patients presenting with post-anastomotic urethroplasty strictures (assessed on history and medical record), * Patients with post-TURP strictures * Patients with neurogenic bladder * Patients with prior history of steroid use * Patients with extravasation during optical internal urethrotomy

Locations (1)

Armed Force Institute of Urology

Rawalpindi, Punjab Province, Pakistan

Outcomes

Primary Outcomes

Recurrence of Urethral Stricture

Number of patients presenting with recurrence of urethral stricture after direct vision internal urethrotomy

Time frame: 6 months post-operatively

Data from ClinicalTrials.gov

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