This study aim to investigate whether the prognosis of eyelid malignant tumor is better treated with Mohs surgery combind with cryotherapy than Mohs surgery only.
This study is a randomized perspective study. American Joint Committee on Cancer was applied to define the cancer stage of patients recruited. Patients with Tis to T3cN0M0 will be randomized to receive Mohs surgery or Mohs suregery conbind cryotherapy. Patients will be followed for 3 years.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
120
Mohs surgery of eyelid
cryotherapy of eyelid
Zhongshan Ophthalmic Center
Guangzhou, Guangdong, China
RECRUITINGrecurrence rate of tumor
measure the tumor recurrence rate for the two groups at three years
Time frame: three years
progression rate of tumor
measure the tumor progression rate for the two groups at three years
Time frame: three years
all cause mortailty
measure the mortality rate for the two groups(Cancer-related death and non-Cancer-related death) at three years
Time frame: three years
side effects of Mohs surgery and cryotherapy in the treatment of eyelid malignant tumor
numbers of participants with side effects
Time frame: three years
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