TPVB, PECSB, ESPB for Postmastectmy Pain

Menoufia University80 enrolled

Overview

Aim of the work The aim of the study is to compare between the effects of ultrasound guided thoracic paravertebral block, pectoral nerve block II, and erector spinae block in management of pain during cancer breast surgeries. The hypothesis of the study is that the three groups will give comparative results.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

DOUBLE

Enrollment

Conditions

Pain, Postoperative

Interventions

Ultrasound guided blockPROCEDURE

Giving one regional block

IV morphineDRUG

given when VAS\>3

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. ASA physical status classification class I or II 2. Age group 18 - 60 years of the female gender 3. Patients undergoing breast cancer surgeries Exclusion Criteria: 1. Patient refusal 2. History of hypersensitivity to local anesthetics 3. Bleeding disorders or patients receiving anticoagulants 4. Spine or chest wall deformities 5. Pregnancy 6. Local infection at the site of injection.

Locations (1)

Faculty of Medicine Menofia University

Shibīn al Kawm, Menofia, Egypt

Outcomes

Primary Outcomes

The primary outcome of the study will be duration of analgesia (time to first rescue analgesia after administration of the block).

minutes

Time frame: 0-24o minutess

Secondary Outcomes

Postoperative pain

assessed by VAS score (0-10) where 0=no pain and 10=worst pain

Time frame: 48 hours

Total morphine consumption

recorded postoperatively in mg

Time frame: 48 hours

Postoperative nausea and vomiting (PONV)

4 points score of PONV (0-3) where 0=no PONV and 3=vomiting more than once

Time frame: 48 hours

Data from ClinicalTrials.gov

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