Evaluation of Renal Damage After PCNL and ESWL Using Novel RNA Based Biomarkers

Inclusion Criteria: * Inclusion criteria for patients : 1. Patients undergoing treatment for a stone(s) located in the kidney less than 2 cm 2. Radiopaque stone 3. Able and willing to give informed consent Inclusion criteria for Healthy volunteers 1. No history of kidney or stone disease 2. Asymptomatic 3. No indwelling ureteral stent 4. Willing to provide medical history information 5. Able and willing to give informed consent Exclusion Criteria: * Exclusion criteria for patients 1. Active urinary tract infection 2. Bleeding disorder 3. Chronic renal failure (eGFR\<30) 4. Ureteral stone