Immune Fitness Prediction

Société des Produits Nestlé (SPN)90 enrolled

Overview

The overall objective of the study is to determine whether self-rated, perceived immune fitness (using questionnaire) is associated with biological assessment of immune fitness (immune signatures in the blood).

Study Type

OBSERVATIONAL

Enrollment

Conditions

Healthy Adults

Eligibility

Sex: ALLMin age: 35 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Ability to understand and sign the informed consent 2. Healthy adult men and/or women, 35-65 years old 3. BMI \>18 and \<30 kg/m2 Exclusion Criteria: 1. Volunteer who cannot be expected to comply with the protocol 2. Individuals with self-reported chronic disease; or who have any clinical condition which the investigator deems relevant for exclusion from the study, 3. Individuals with an impaired immune system that may confound immune response testing; i.e. any condition that impairs participant immune response through either the condition itself or through the treatment of the condition, 4. Family or hierarchical relationships with Clinical Innovation Lab at Nestlé Research, Lausanne, Switzerland

Locations (1)

Nestlé Clinical Research Unit

Lausanne, Canton of Vaud, Switzerland

Outcomes

Primary Outcomes

Percentage of different immune cell types in whole blood

Immune cell type profiling in whole blood by mass cytometry

Time frame: 6 - 12 months after the start of the trial

Relative quantification of immune protein in plasma

Proteomic analysis in plasma by proximity extension assay

Time frame: 6 - 12 months after the start of the trial

Amount of cytokines expressed by peripheral blood mononuclear cells

Cytokine quantification by proximity extension assay

Time frame: 6 - 12 months after the start of the trial

Amount of analytes in serum

Blood chemistry

Time frame: 6 - 12 months after the start of the trial

Data from ClinicalTrials.gov

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