Multicenter Validation of the PREDICT Score

Mansoura University262 enrolled

Overview

Even after adequate TME with grade III mesorectal grading, local recurrence remains a possible event. Several studies investigated different parameters and assessed their predictive power in regards to local recurrence after TME. These parameters included a variety of patient-related, tumor-related, and treatment-related factors. A recent meta-analysis reviewed the current literature for the predictors of local recurrence after TME for rectal cancer and developed a prognostic scoring system, the PREDICT score. The present study aimed to validate the PREDICT scoring system by applying it to a prospective cohort of patients with rectal cancer who underwent curative TME in three

Study Type

OBSERVATIONAL

Enrollment

262

Conditions

Rectal Cancer

Interventions

PREDICT scoreDIAGNOSTIC_TEST

Predictive score for local recurrence after TME for rectal cancer that includes 8 parameters

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adult patients of either sex with non-metastatic low or middle rectal cancer who underwent elective TME with curative intent Exclusion Criteria: * Patients with recurrent or metastatic rectal cancer at the time of presentation * Patients with synchronous colon cancer * Patients with missing data on the outcome of TME.

Locations (1)

Mansoura university hospital

Al Mansurah, Dakahlia Governorate, Egypt

Outcomes

Primary Outcomes

Sensitivity of PREDICT score

The ability of the score to predict actual cases of recurrence after TME

Time frame: 36 months after surgery

Specificity of PREDICT score

The ability of the score to predict patients who did not experience recurrence after TME

Time frame: 36 months after surgery

Data from ClinicalTrials.gov

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