Study of Trans Sodium Crocetinate in Patients With Interstitial Lung Disease

Inclusion Criteria: 1. Male or Female, age 30 to 85 years at screening 2. Able to provide informed consent and agree to adhere to all study visits and requirements 3. Females of childbearing potential must have a negative blood pregnancy test at screening and agree to use one of the accepted contraceptive regimens, or a double method of birth control during the study and at least 30 days after the last dose of study drug 4. Established diagnosis of ILD (clinical, radiographic, or histologic) 5. SpO2 ≥ 88% at rest by pulse oximetry while breathing ambient air 6. Free of any active cardiovascular or neuromuscular disease, at PI discretion 7. Clinically stable disease with no major medication changes in the last 4 weeks 8. Forced vital capacity (FVC) ≥ 45% of predicted (within past 6 months) 9. DLCO corrected for hemoglobin 30-90% of predicted, inclusive (within past 6 months) 10. Sars-CoV-2 negative at screening Exclusion Criteria: 1. Known allergy to study medication 2. Pregnancy or lactation 3. Current smoker 4. Inability to perform pulmonary function testing 5. Active infection at screening or day of study visit 6. Known pulmonary hypertension (PH) requiring PH-specific treatment 7. AST/ALT ≥ 3x ULN and/or total bilirubin ≥ 2x ULN 8. Received any investigational medicine (IMP) within past 30 days 9. Surgery or hospitalization in past 3 months determined by the PI to be clinically relevant. 10. Current alcohol or substance abuse 11. Known active or latent hepatitis B or C 12. History of end-stage liver or renal disease 13. Positive COVID test anytime within 3 months of screening. Note: Patients who were previously vaccinated for COVID are allowed 14. History of venous thromboembolic disease 15. History of acute or chronic ophthalmologic conditions currently requiring treatment