A faster emergence from general anesthesia has a double medico-economic impact by reducing the risks of complications and optimizing the performance of surgical units. No drug has been retained for its ability to actively accelerate anesthetic emergence by antagonizing hypnotics. Thus, the aim of this study was to examine the effect of caffeine on the time to emerge from sevoflurane anesthesia for laparoscopic cholecystectomy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
At the end of the surgery, the study drug was given intravenously over ten minutes than the sevoflurane infusion was stopped corresponding to the start of the recovery period
At the end of the surgery, the placebo was given intravenously over ten minutes than the sevoflurane infusion was stopped corresponding to the start of the recovery period
Habib Thameur Hospital
Tunis, Tunisia
RECRUITINGanesthetic recovery time
time to return to spontaneous breathing, eye opening on verbal command and time for extubation
Time frame: Postoperative
plasma caffeine levels at H1 and H24
Time frame: Hour 1 and Hour 24
postoperative rehabilitation
incidence of headache, nausea and vomiting, tiredness score, time to the first flatus and satisfaction of patients
Time frame: 24 hours postoperatively
postoperative pain (Visual Analog Scale score 0 "no pain" to 10 "severe pain") and consumption of morphine
Time frame: 24 hours postoperatively
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.