This study aims to 1. To study the prognostic value of LUS in COVID-19 patients. 2. To assess the relation between Lung Ultrasonography Score and disease severity in COVID-19 Patients. 3. To assess the relation between Lung Ultrasonography Score and mortality in COVID-19 patients.
At the end of 2019, the COVID-19 pandemic broke out in Wuhan, China, and within few months -in March 2020- it was declared a pandemic by the WHO. As of September 15th ,2021, there have been 226,844,344 confirmed cases of COVID-19, including 4,666,334 deaths, reported to WHO (1). Due to the prevalence of COVID-19 and the financial burden it puts on the healthcare system, the use of a simple, affordable and reliable imaging modality was necessary. The main idea in this research will be evaluating the value of Lung Ultrasonography Score in predicting the prognosis of patients with COVID-19 pneumonia and investigate the presence of a relation between the Lung Ultrasonography Score and patients' prognosis and mortality (2). * Currently, Lung ultrasound had sensitivity 86%, specificity 71.6%, NPV 81.7%, and PPV 77.7%. The LUS had an area under the curve of 0.84 (95% CI 0.78, 0.90). When including examinations visualizing twelve lung areas, lung US had sensitivity 90.9% and specificity 75.6%, with NPV 87.2% and PPV 82.0% and an area under the curve of 0.89 (95% CI 0.83, 0.96). (3). * In COVID-19 patients admitted in ED, LUS was a good predictor of death, ICU admission, and endotracheal intubation. * Our main strategy will be enrolling patients admitted to the chest department's isolation unit, conduct clinical examination, laboratory investigations and imaging and conduct chest ultrasonography and calculate the Lung Ultrasonography Score of the patients and create a correlation between the Lung Ultrasonography score and their prognosis and mortality.
Study Type
OBSERVATIONAL
Enrollment
60
The ultrasonography will be done using the curved probe of the SONOACE R3 SAMSUNG ultrasonography machine, SN: S0GYM3HCC00016M, manufacture date: 12-2012. Assessment of lung condition using the Lung Ultrasonography Score (total score calculated from the 12 standard examined areas, from 0 to 3 in each area, with a minimum of 0 up to 36)
Assiut University Hospital
Asyut, Egypt
RECRUITINGCorrelation between Lung Ultrasonography Score and condition severity (inflammatory markers)
creation of a statistical relation between the Lung Ultrasonography Score and the severity of the condition, which is assessed by clinical examination and inflammatory markers.
Time frame: through study completion, an average of 2 years.
Mortality
creation of a statistical relation between the Lung Ultrasonography Score and mortality.
Time frame: Through study completion, an average of 2 years.
Ventilatory support.
creation of a statistical relation between the Lung Ultrasonography Score and the ventilatory support needed by the patients.
Time frame: Through study completion, an average of 2 years.
Duration of hospital stay
Assessment of relation between Lung Ultrasonography Score and the duration of hospital stay.
Time frame: Through study completion, an average of 2 years.
ICU Admission
Assessment of relation between Lung Ultrasonography Score and the ICU admission.
Time frame: Through study completion, an average of 2 years.
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.