Patients with idiopathic macular holes (MHs) postoperative closure rates for large MHs (diameter \> 550 μm) are disappointing and often require a second intervention, different techniques have been described with very variable success rates in different published studies, an efficient technique with good functional outcome has not been found.
Interventional study in large macular holes (diameter \> 550 μm) using an amniotic membrane with and without internal limiting membrane peeling.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
16
Pars plana vitrectomy with/without internal limiting membrane peeling, amniotic membrane, and air tamponade
Instituto de Oftalmologia Conde de Valenciana
Mexico City, Mexico
RECRUITING% of macular hole clousure measured with OCT
Closure of the macular hole by optical coherence tomography
Time frame: 6 months
Best-corrected visual acuity measured with Snellen Chart
Improvement of 2 lines in best-corrected visual acuity
Time frame: 6 months
Superficial and deep retinal capillary plexus density with OCT-A
Presence of capillary plexus in macular hole area
Time frame: 6 months
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