The aim of this study is to investigate whether researchers can improve sleep quality in patients with deep brain stimulators by delivering targeted stimulation patterns during specific stages of sleep.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
4
Open and closed-loop electrical modulation triggered and based on ongoing sleep staging by researcher as well as automated closed-loop algorithm for stimulation.
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Participants to Complete Study
Total number of participants to complete all scheduled study activities
Time frame: Through study completion, approximately 1 year
Total Sleep Time
Length of sleep time reported in minutes
Time frame: Baseline, post-intervention (approximately 1 night)
Psychomotor Vigilance Test
Measures reaction time (milliseconds) by asking subjects to press a button on an electronic device as soon as a light appears (every few seconds for 10 minutes).
Time frame: Baseline, post-intervention (approximately 1 night)
Karolinska Sleepiness Scale
Measures subjective level of tiredness at a particular time during the day using a 9-point scoring scale of 1 = extremely alert, 3 = alert, 5 = neither alert nor sleepy, 7 = sleepy - but no difficulty remaining awake, and 9 = extremely sleepy - fighting sleep.
Time frame: Baseline, post-intervention (approximately 1 night)
Latency to Sleep Onset
Time in minutes from beginning of study to the first stage of sleep
Time frame: Baseline, post-intervention (approximately 1 night)
Latency to Rapid Eye Movement (REM) Sleep
Time in minutes from beginning of sleep to first REM sleep onset.
Time frame: Baseline, post-intervention (approximately 1 night)
Number of Sleep Cycles
Total number of sleep cycles defined as switches of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep.
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Time frame: Baseline, post-intervention (approximately 1 night)
Number of Awakenings Per Night
Total number of awakenings during night
Time frame: Baseline, post-intervention (approximately 1 night)