Title: Povidone-soaked Sutures Versus Ordinary Sutures for Reducing Surgical Site Infection

Universiti Sains Malaysia140 enrolled

Overview

To determine efficacy of using 3 minutes povidone-soaked suture in reducing surgical site infection during wound closure in elective surgery.

Participant recruitment and randomisation based on eligibility based on CONSORT. Patient will get either package A or B which determine whether they are getting povidone-soaked suture or ordinary suture during wound closure. Postoperative, follow up on D10 and D30 of patient well being and signs and symptoms of surgical site infection

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

DOUBLE

Enrollment

140

Conditions

Efficacy Povidone Soaked Suture in Reducing Surgical Site Infection

Interventions

povidone-soaked sutureOTHER

suture soak with povidone solution for 3 mins

ordinary sutureOTHER

suture no need to soak with povidone solution

Eligibility

Sex: ALLMin age: 12 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age more than 12 years old * Clean surgery or Clean- contaminated surgery * Elective surgery Exclusion Criteria: * Age less than 12 years old * Contaminated wound * Dirty wound * Allergy to povidone-iodine * Pregnant * Laparoscopic * Emergency surgery

Locations (1)

Universiti Sains Malaysia

Kubang Kerian, Kelantan, Malaysia

Outcomes

Primary Outcomes

Povidone-soaked Sutures versus Ordinary Sutures for Reducing Surgical Site Infection: Randomize Control Trial Study in General Surgery Cases of Hospital Universiti Sains Malaysia

There is difference of outcome using povidone-soaked suture and ordinary suture. In this study, our hypothesis the suture with povidone-soaked will reduce the SSIs rate during closure and it will be assessed on day 10 and day 30 post-operative. Few measurement are used in detection of SSI based on clinical and biochemical measurement such as signs of inflammation and total white cell count.

Time frame: 6 months

Secondary Outcomes

Povidone-soaked Sutures versus Ordinary Sutures for Reducing Surgical Site Infection: Randomize Control Trial Study in General Surgery Cases of Hospital Universiti Sains Malaysia

There is association between povidone-soaked suture and ordinary suture in reducing surgical site infection. There is difference of outcome using povidone-soaked suture and ordinary suture. In this study, our hypothesis the suture with povidone-soaked will reduce the SSIs rate during closure and it will be assessed on day 10 and day 30 post-operative. Few measurement are used in detection of SSI based on clinical and biochemical measurement such as signs of inflammation and total white cell count.

Time frame: 6 months

Povidone-soaked Sutures versus Ordinary Sutures for Reducing Surgical Site Infection: Randomize Control Trial Study in General Surgery Cases of Hospital Universiti Sains Malaysia

There is difference in the extent of intervention needed to manage SSIs in wounds closed with povidone-soaked suture and ordinary suture. This hypothesis measure how far that the management of SSIs whether non-operative or operative treatment is needed. This is base on antibiotic use, dressing and surgical intervention such as debridement.

Time frame: 6 months

Data from ClinicalTrials.gov

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