Acute appendicitis is a common and potentially serious medical condition which can be difficult to diagnose, especially in pediatric patients. To help recognize patients with acute appendicitis, number of laboratory and radiological test are used. Previous research has shown that Circulating Human Leucine-rich α-2-glycoprotein (LGR1) in the blood can be elevated in pediatric patients with acute appendicitis. The aim of this research is to analyse whether LGR1 levels in saliva can be used as a less invasive diagnostic method in pediatric patients with suspected acute appendicitis.
Study Type
OBSERVATIONAL
Enrollment
90
Blood specimen collection for analysis of CRP (C-reactive protein), WBC (White blood cells) and LRG1 (Circulating Human Leucine-rich α-2-glycoprotein) levels
Saliva specimen collection for analysis of LRG1 (Circulating Human Leucine-rich α-2-glycoprotein) levels
University Hospital Split
Split, Split-Dalmatia County, Croatia
RECRUITINGLevel of LGR1 protein in blood
Levels of LGR1 protein in blood and saliva as measured by ELISA test
Time frame: 72 hours
Level of LGR1 protein saliva
Levels of LGR1 protein in saliva as measured by ELISA test
Time frame: 72 hours
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