Evaluation of Sublingual Microcirculation in Burn During Resuscitation

Cairo University30 enrolled

Overview

The adequacy of fluid resuscitation will be monitored in burn patients using microcirculation. Microcirculation camera will be placed on the base of the tongue and at different four quadrants. • Microcirculation parameters at baseline and after 8h , 16h and 24h of fluid resuscitation will be recorded. Fluid resuscitation with lactated ringer according to Parkland formula (4 ml/kg/%TBSA) 50% given during the first 8 hours, with the remainder given during the following 16 hours, will be initiated to maintain a urinary output of 0.5ml/kg/hr.Norepinephrine infusion will be started in case of circulatory failure at a rate of 0.02mic/kg/min to maintain MAP of 65-70mmHg.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Burn Shock

Interventions

Microcirculation cytocamDEVICE

Visualization of tongue microcirculation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age more than 18 years old * Burn \>20% TBSA * Patients with burn admitted within the 1st 6 hours Exclusion Criteria: * Age \< 18 years old. * Pregnant patients. * Patients with severe renal insufficiency. * Patients shocked due to other causes as sepsis, hypovolaemia or cardiogenic shock * Patients with airway edema that preclude the measurement of sublingual microcirculation

Outcomes

Primary Outcomes

• Lactate level

mmol/L

Time frame: 24 hours

Secondary Outcomes

total vessel density

mm/mm2