The study aims to determine if genotype-based nutrition and lifestyle advice is effective for the management of overweight and obesity among Filipino adults compared to the usual standard of care.
The primary objective of the study is to determine if providing a nutrition and lifestyle advice with genetic information can promote the attainment of 5-10% weight loss, and improvements on body mass index, waist circumference, and body fat percentage among Filipino adults with overweight and obesity. Additionally, changes in dietary intake, eating behaviour, physical activity level, biochemical parameters (HbA1c and blood lipid profile), motivation for weight loss, and knowledge and perceptions on nutrigenomics and genetic testing will also be assessed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
62
This group will receive Nutrition and Lifestyle recommendation based on SNPs known to have an impact to body weight and body composition, and responses to physical activity and dietary fat intake
This group will receive the conventional and standard nutrition lifestyle recommendation for weight management
Department of Science and Technology-Food and Nutrition Research Institute
City of Taguig, National Capital Region, Philippines
5% weight loss
Attainment of 5% weight loss
Time frame: 24 weeks
10% weight loss
Attainment of 10% weight loss
Time frame: 48 weeks
Body mass index
Changes in BMI
Time frame: 24 weeks
Waist circumference
Changes in waist circumference
Time frame: 24 weeks
Body fat percentage
Changes in body fat percentage
Time frame: 24 weeks
Dietary intake
Improvements in dietary intake
Time frame: 24 weeks
Eating behavior
Improvements in eating behavior
Time frame: 24 weeks
Physical activity level
Improvements in physical activity level
Time frame: 24 weeks
Glycated haemoglobin (HbA1c)
Changes in HbA1c
Time frame: 24 weeks
Blood lipid profile (TC, LDL-C, HDL-C, Triglycerides)
Changes in TC, LDL-C, HDL-C, Triglycerides
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Time frame: 24 weeks
Motivation for weight loss
Stages and motivation for weight loss
Time frame: 24 weeks
Knowledge and perceptions
Knowledge and perceptions in nutrigenomics and genetic testing
Time frame: 24 weeks