Colonoscopic removal of polyps is an important and well-established tool in the prevention of colorectal cancers. However, high polyp recurrence rates after endoscopic resection, with resultant development of interval cancers, remains a problem; this most commonly stems from unrecognised incomplete polyp resection. Thus, a standardised endoscopic technique is needed that will allow endoscopists to consistently achieve a clear margin of resection. The investigators believe the Cap Assisted Resection Margin Assessment (CARMA) technique will address this problem. This novel technique focuses on a standardised assessment of the resection margin after endoscopic polypectomy utilising available standard high-definition video endoscopes with imaging features including narrow band imaging (NBI) and magnification endoscopy.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Once standard polyp resection and assessment of the polypectomy site without magnification is completed, the CARMA technique will be applied. This will involve an assessment of the entire polypectomy margin using cap assisted magnification endoscopy with the ability to also use NBI (at the endoscopist's discretion) and documentation of any residual polyp noted.
Princess Alexandra Hospital
Woolloongabba, Queensland, Australia
RECRUITINGRate of achieving a clear resection margin using the CARMA technique
Time frame: Established during index procedure
Sensitivity and specificity of the CARMA technique for residual polyp detection
Time frame: Established during index procedure
Frequency of residual polyp without CARMA assessment
Time frame: Established during index procedure
Incomplete resection rate with use of CARMA technique
Time frame: Established during index procedure
Incomplete resection rate with use of the CARMA technique in polyps > 10mm with hot snare
Time frame: Established during index procedure
Incomplete resection rate with use of the CARMA technique in polyps > 10mm with cold snare
Time frame: Established during index procedure
Residual polyp rate after CARMA technique with hot snare
Time frame: Established during index procedure
Residual polyp rate after CARMA technique with cold snare
Time frame: Established during index procedure
Time required for application of the CARMA technique with < 10mm
Time frame: Established during index procedure
Time required for application of the CARMA technique with > 10mm
Time frame: Established during index procedure
Polyp recurrence rate for < 10mm polyps
Time frame: Established during surveillance procedure (following national guidelines - between 6 months to 5 years)
Polyp recurrence rate for > 10mm polyps
Time frame: Established during surveillance procedure (following national guidelines - between 6 months to 5 years)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.