Protocols for Prevention of PPH During CS in High Risk Group

Assiut University448 enrolled

Overview

PPH is one of the most leading causes of maternal mortality,. It means loss of 500 ml blood after vaginal delivery and 1000 ml blood after cesarean delivery. Although it's preventable it represents about 27%of maternal deaths. Atony is the main cause of PPH. 70%of PPH corresponds to uterine atony. Uterotonics like oxytocin, misoprostol, ergometrine, carbetocin and combinations of these drugs can be used but until now there is no agreement on medication that can be the most effective.

Study Type

OBSERVATIONAL

Enrollment

448

Conditions

Atonic PPH

Interventions

Syntocinon, papal, misotacDRUG

Using different drugs to prevent atonic PPH during CD in high risk group

Eligibility

Sex: FEMALEMin age: 19 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * 1\. Pregnant full term\>37 w 2. Maternal age 19- 40 3.physical state 1\&2 4.patient willing to enter the study Exclusion Criteria: * 1.who refuse to participate in study 2.immunocomprmized and patients who had contraindicated from any of drugs used 3.patients with hypersensitivity to any drug

Outcomes

Primary Outcomes

Amount of blood loss

Decrease amount of blood loss

Time frame: 1 year

Secondary Outcomes

Finding the drug most effective with least adverse effects

Time frame: 1 year

Data from ClinicalTrials.gov

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