This is a single-arm, single-center phase II clinical study to explore the efficacy and safety of sintilimab combined with concurrent chemoradiation therapy as treatment in women with locally advanced cervical cancer.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
20
IV infusion
IV infusion
Undergo pelvic EBRT
The Affiliated Hospital of Xuzhou Medical University
Xuzhou, Jiangsu, China
RECRUITINGOverall response rate
The proportion of patients with at least one tumor scan of complete response (CR) or partial response (PR) using RECIST v1.1
Time frame: 1 year
Progression free survival
2 years
Time frame: Time from diagnosis of disease to disease progression or death due to any cause
Overall survival
2 years
Time frame: Time from diagnosis of disease of treatment until death due to any cause
Incidence of ADRs and tolerance
Time frame: 1 years
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brachytherapy