It is a single-arm, open-label clinical study to assess the safety and efficacy of the Anti-CD19 Universal CAR-T Cells injection for patients with CD19+ refractory/relapsed B cell acute lymphoblastic leukemia and B cell non-Hodgkin lymphoma.
The study consists of the following periods: screening, lymphodepletion, CAR-T cell infusion, safety follow up, and long term follow-up.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
15
Anti-CD19 Universal CAR-T Cells injection will be administered by vein after lymphodepletion.
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
Kunming, Yunnan, China
RECRUITINGDose Limiting Toxicities
Incidence of dose-limiting toxicities as protocol-defined
Time frame: Up to 4 weeks after CAR-T infusion
Objective response rate (ORR)
Objective response rate after CAR-T infusion
Time frame: At 4,12,24 weeks after CAR-T infusion
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