Umbilical Cord Mesenchymal Stem Cell Transplantation for Decompensated Hepatitis B Cirrhosis

Inclusion Criteria: * Aged between 20 and 60 (male or female) * Diagnosed chronic decompensated hepatitis B cirrhosis with a course of more than 5 years * Not suitable for liver transplantation or there is no donor liver source * No serious bleeding tendency or active bleeding * No hepatic encephalopathy * After strict medical conservative treatment for more than 6 months, there was no relief of symptoms or significant improvement of quality of life score * Subjects voluntarily participate in this study and sign informed consent Exclusion Criteria: * Be less than 20 years old or more than 60 years old * Cirrhosis caused by other causes such as alcoholic hepatitis, hepatitis C virus and autoimmune hepatitis * Found liver malignant tumor or the family history of liver malignant tumor in the third generation of their direct relatives * Patients with hypersplenism who need splenectomy * History of tumors in other organs * PT prolongation is greater than 3 seconds * Use of human serum albumin within 3 weeks prior to clinical registration * Clinically significant upper gastrointestinal bleeding events occurred within 4 weeks before clinical registration * Spontaneous peritonitis * Active infection (viral or bacterial) * Pregnant or lactating women * The researcher considers it inappropriate to participate in this study