Dark Halo and MNV: a Study Between ICGA and OCTA

Federico II University50 enrolled

Overview

The aim of study is to compare the evaluation of dark halo area of macular neovascularization (MNV) between indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA) in order to identify OCTA as effective and useful biomarker in MNV

Dark halo is defined as a dark perilesional of flow decrease due to an area of reduced choroidal flow adjacent to the macular neovascularization (MNV). The detection of MNV vascular details was only possible through invasive dye injection, such as fluorescein angiography (FA) or indocyanine green angiography (ICGA). Optical coherence tomography angiography (OCTA) is a recent imaging technique that is able to detect the perfusion and non-perfusion areas carefully. The aim of study is to compare the evaluation of dark halo area of MNV between ICGA and OCTA

Study Type

OBSERVATIONAL

Enrollment

Conditions

Macular Neovascularisation

Interventions

Optical Coherence Tomography Angiography (OCTA) and indocyanine green angiography (ICGA)DIAGNOSTIC_TEST

OCTA and ICGA is able to detect the dark halo as a area of reduced perfusion around MVN

Eligibility

Sex: ALLMin age: 55 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age older than 55 years * diagnosis of macular neovascularization * absence of previous treatment with anti-Vegf injections * absence of other retinal vascular diseases Exclusion Criteria: * age younger than 55 years * absence diagnosis of macular neovascularization * presence of previous treatment with anti-Vegf injections * presence of other retinal vascular diseases

Locations (1)

University of Naples "Federico II"

Naples, Italy

Outcomes

Primary Outcomes

Dark halo measurement

The OCTA and ICGA parameters analyzed are: the area of dark halo (mm2) that surrounds the coroidal neovascularization.

Time frame: three years

Data from ClinicalTrials.gov

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