Risk Stratification Using Midregional Proadrenomedullin in the ED

Inclusion Criteria: 1. Consecutive patients presenting to the ED with suspicion of infection 2. Age ≥18 years 3. Written Informed Consent obtained Exclusion Criteria: 1. Patients with SARS-COV-2 infection 2. Recent major trauma or surgery 3. End stage renal failure requiring dialysis 4. Terminal disease and/or very severe medical co-morbidity where death has to be expected in the next 6 months, e.g. due to malignancy, cardiac, renal or hepatic failure 5. Patients whose source of infection always requires hospital admission or never requires hospital admission. 6. Patients who cannot be discharged for other than medical reasons 7. Patient participates in any other interventional clinical trial 8. Patients with active abusive drug use 9. Pregnant or lactating women 10. Patients who are institutionalized by official or judicial order 11. Dependents of the sponsor, the CRO, the study site or the investigator