Prevalence of Pharyngolaryngeal Reflux in Patients Treated for Obstructive Sleep Apnea Syndrome

Elsan37 enrolled

Overview

The aim of the study is to find, using validated and efficient tools, a laryngopharyngeal reflux in patients receiving polysomnography for suspected obstructive sleep apnea syndrome. It is proposed to carry out simultaneously, at the Sleep Center of the Polyclinique of Poitiers (CSPP), a polysomnography, a 24-hour Restech pharyngeal pH-metry (day and night), a Peptest (in the evening and in the morning of the polysomnography), with the RSS-12 questionnaire and the RSA score.

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Obstructive Sleep Apnea Reflux, Laryngopharyngeal

Interventions

PolysomnographyDIAGNOSTIC_TEST

A polysmnography is planned for every patients in order to evaluate the Apnea-Hypopnea Index (AHI).

Pharyngeal ph-metry RestechDIAGNOSTIC_TEST

Pharyngeal ph-metry Restech over 24 hours (night and day)

PeptestPROCEDURE

Saliva sample to look for an association between pharyngolaryngeal reflux and obstructive sleep apnea syndrome

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Adults (\> 18 ans) * Polysomnography planned for OSA assessment * RPL known or not, suspected or not * Affiliation to a social security scheme or beneficiary of such a scheme * Patient having signed the free and informed consent Exclusion Criteria: * Minors * Smoking, alcoholism, chronic or serious disabling pathology * Medical history of upper aerodigestive tract cancer, radiotherapy * Recent infection of upper aerodigestive tract, chronic rhinosinusitis * Permanent nasal obstruction * Active allergy * Non-obstructive SAS (central) * Patient under anti-secretory treatment (IPP) during the 8 days preceding the Restech associated with the PSG * Refusal to participate in the study * Protected patients: Adults under guardianship, guardianship or other legal protection, deprived of liberty by judicial or administrative decision * Pregnant, breastfeeding or parturient * Hospitalized without consent

Locations (1)

Centre du Sommeil de la Polyclinique de Poitiers

Potiers, France

Outcomes

Primary Outcomes

Proportion of patients with Obstructive Sleep Apnea Syndrome diagnosed with pharyngolaryngeal reflux.

the diagnosis of OSA is posed by the PSG as soon as the AHI is ≥ 15 / h

Time frame: 3 months

Secondary Outcomes

RSS-12 score

Positive (\>11)

Time frame: 3 months

RSA score

Positive if \> 14

Time frame: 3 months

Peptest

Positive if \> 75 ng / mL

Time frame: 3 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.