Correlation Between Pupil Size and Ocular Signs of Pseudoexfoliation Syndrome

Assiut University100 enrolled

Overview

To study possible correlation between the size of the pupil in both room light and after dilation between both eyes in bilateral pseudoexfoliation with Intraocular pressure, lens clarity and stability, Optic disc , Visual changes and glaucoma changes by optical coherence tomography

For each patient. Full preoperative ophthalmological assessment will be done using slit lamp , size of the pupil in regular room light (usually around 2000 Lux) and post dilation with tropicamide 1%. baseline IOP measurement using Goldmann applanation tonometer, UCDVA (Uncorrected Distance Visual Acuity)and CDVA (Corrected Distance visual acuity), lens opacification or clarity, stability or subluxation. corneal endothelial cell count. Fundus examination using 90 D or 78D lenses, Humphrey visual field (24-2) analysis and optical coherence tomography on retinal nerve fiber layer (RNFL) and ganglion cell complex.(GCC)

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Pseudoexfoliation Syndrome Pseudoexfoliation Glaucoma in Both Eyes Pseudoexfoliation of Lens; Glaucoma

Interventions

, Humphrey visual field (24-2) analysis and optical coherence tomography on retinal nerve fiber layer (RNFL) and ganglion cell complex.(GCC)DIAGNOSTIC_TEST

, Humphrey visual field (24-2) analysis and optical coherence tomography on retinal nerve fiber layer (RNFL) and ganglion cell complex.(GCC)

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: All patients with pseudoexfoliation syndrome Exclusion Criteria: previous ocular surgery or ocular trauma affecting pupil. Any systemic or neurologic disease affecting pupil

Locations (1)

Assiut University

Asyut, Egypt

Outcomes

Primary Outcomes

correlation between pupil size and severity of Pseudoexfoliation

in each eye of the same patient we study correlation between pupil size with ntraocular pressure, lens status, corneal endothelial count and glaucomatous damage represented by (optic disc changes (cup to disc ratio) and OCT changes (RNFL and GCC)

Time frame: 2-3 months

Data from ClinicalTrials.gov

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