Arthroscopic partial meniscectomy(APM) surgery outcomes for Metabolic Syndrome(MetS) patients with degenerative meniscus tears(DMTs) was still not clear. The aim of the study was to investigate outcomes of early APM vs delayed APM for MetS patients with degenerate meniscus tears.
Degenerate meniscus tears(DMTs) were the most common knee disease in aged and obese people. The most common treatment for DMTs was arthroscopic partial meniscectomy(APM) surgery. However, the time window for performing APM surgery was unclear, especially in obese patients with Metabolic syndrome(MetS). Abdominal obesity, insulin resistance with or without glucose intolerance, dyslipidemia or elevated blood pressure are included in the principal components of MetS. Whether early APM within 3 to 6 months or delayed APM surgery within 6 to 12 months are benefical to MetS patients with DMTs. The knee function outcomes between early APM and delayed APM for MetS patients with DMTs were assessed and follow up to 12 months after surgery.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
120
Early APM group were patients have knee syndrome within 3 to 6 months
delayed APM group recruit participants who received delayed APM surgery within 6 to 12 months
First Affiliated Hospital of Jinzhou Medical University
Jinzhou, Liaoning, China
RECRUITINGKnee KOOS score
The KOOS was a self-administered outcome questionnaire has been validated in individuals undergoing APM surgery,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month
IKDC score
The IKDC was a questionnaire that has high reliability and validity for middle to older patients with a meniscal tear,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month
waist circumstance
midway between the lowest rib and the iliac crest, using an anthropometric tape
Time frame: at baseline
SBP
systolic blood pressure
Time frame: at baseline
DBP
diastolic blood pressure
Time frame: at baseline
TC
serum total cholesterol (TC)
Time frame: at baseline
TG
serum triglycerides (TG)
Time frame: at baseline
LDL
serum low-density lipoprotein cholesterol (LDL-C)
Time frame: at baseline
HDL
serum high-density lipoprotein cholesterol (HDL-C)
Time frame: at baseline
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FBG
serum fast blood glucose(FBG)
Time frame: at baseline
BMI
BMI, calculated as weight in kilograms divided by height in meters squaredBMI in kg/m\^2
Time frame: at baseline
K-L grade
Kellgren-Lawrence (K/L) grade
Time frame: at baseline
pain score
The KOOS subscales for pain,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month
symptoms score
The KOOS subscales for symptoms,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month
activities of daily living score
The KOOS subscales for activities of daily living,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month
function in sport and recreation score
The KOOS subscales for function in sport and recreation,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month
knee related quality of life score
The KOOS subscales for knee related quality of life,with 0(extreme knee problem) to 100 points(the best possible score, no knee problems)
Time frame: up to 12 month