The best way to titrate positive end-expiratory pressure (PEEP) in patients suffering from acute respiratory distress syndrome is still matter of debate. Electrical impedance tomography (EIT) in a non-invasive technique that could guide PEEP setting based on an optimized ventilation homogeneity.
COVID-19 related ARDS patients admitted to the ICU in March 2021 requiring mechanical ventilation were enrolled. Patients were monitored by an esophageal catheter and a 32-electrode EIT device. Within 48 hours after the start of mechanical ventilation, different levels of PEEP were applied based upon PEEP/ Fraction of inspired oxygen tables, positive end-expiratory transpulmonary (PL)/ FiO2 table, and EIT. Respiratory mechanics variables were recorded.
Study Type
OBSERVATIONAL
Enrollment
17
PEEP setting according to various methods
Service de Réanimation Médicale, Hôpital Central
Nancy, France
Value of PEEP
different PEEP values obtained through using different methods
Time frame: a single determination, within 24-48 hours after mechanical ventilation initiation
Respiratory mechanics
Respiratory mechanics (plateau pressure, driving pressure, compliance, mechanical power) following different PEEP settings
Time frame: a single determination, within 24-48 hours after mechanical ventilation initiation
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