Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty

Lithuanian University of Health Sciences176 enrolled

Overview

The aim of the study is to determine whether the optimisation of the preoperative nutritional status affects the course of the perioperative period in patients with frailty. Subjects: Patients 65 and over years of age with frailty or risk of it, with suboptimal nutritional status who are prescribed to elective cardiac surgery . Research methods: Edmonton Crispness Scale, a Mini Nutritional Assessment (MNA-SF) test will be used to select subjects. Body composition will be examined by bioelectrical impedance analysis (BIA) to determine the degree of phase angle. Changes in laboratory blood tests will be recorded and evaluated The subjects randomly will be divided into control and study groups. The diet of the patients in the study group will be optimised by protein supplements before elective heart surgery. The benefits of optimising nutritional status will be evaluated comparing laboratory blood tests, changes in organ function, adverse outcomes, the need for vasoactive drugs, artificial lung ventilation time and length of hospitalisation between the groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

176

Conditions

Malnutrition; Protein Frail Elderly Syndrome

Eligibility

Sex: ALLMin age: 65 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients 65 years of age and older. * Patients for whom cardiac surgery will be performed on a scheduled basis. * Patients able to move without the help of others except for an aid: a stick, a walker. * Patients who speak and understand Lithuanian perfectly. * Patients who have read the informed consent form and confirmed their consent to participate in the study in writing. Exclusion Criteria: * Patiens younger than 65 years. * No written consent of a person to participate in a biomedical research has been obtained; * Patients with a history of mental illness or central nervous system disorders that interfere with the perception and proper assessment of their health and the meaning and content of the questionnaire / tasks. * Patients with amputated lower extremities. * Patients with hepatic insufficiency, one or more of viral hepatitis. * It is not possible to perform a qualitative physical examination for other reasons (hearing, vision, etc.) * Allergy to B vitamins.

Influence of Preoperative Nutritional Status on Perioperative Period in Cardiac Surgery in Patients With Frailty

Overview

Conditions

Interventions

Eligibility

Outcomes

Primary Outcomes

Central Contacts