A Single-Arm Objective Performance Criteria Trial for Intracranial Thrombus Aspiration Catheter

Inclusion Criteria: * Age ≥18 years; * Baseline NIHSS score ≥6; * Subject has acute occlusion located in Vertebral artery(VA) / Internal Carotid Artery (ICA) / M1or M2 segment of Middle Cerebral Artery (MCA) / Basilar artery (BA) diagnosed by DSA; * Femoral artery puncture is expected to be completed within 24 hours of onset； * mRS score≤ 2; * Subject or legal representative is able to understand the purpose of study, agrees to comply with protocol requirements and has provided written informed consent. Exclusion Criteria: * Chronic occlusion in the target area; * Epilepsy at the time of stroke； * Bleeding from the gastrointestinal or urinary system in the past three weeks； * After drug control, systolic blood pressure was greater than 185mmhg and / or diastolic blood pressure was greater than 110mmhg; * International Normalized Ratio(INR)\>3; * Random blood glucose \< 2.7mmol/L or \> 22.2mmol/L; * Heart, lung, liver, kidney failure or other serious diseases (such as brain tumors, - systemic infection, active disseminated intravascular coagulation, myocardial infarction within 12 months before enrollment, history of severe mental illness); * Tortuous lesion / severe stenosis in the starting segment of the carotid artery / Carotid dissection / Arteritis judged by researchers that is not suitable for the procedure; * Acute occlusion of bilateral carotid arteries； * Intracranial hemorrhage or massive infarction diagnosed by CT or MR; * History of allergies to antiplatelet drugs, anticoagulants, anesthetics, contrast agents; * Expected life \<12 months; * Female subjects who are pregnant or planning to become pregnant or lactate within the study period; * Subject has participated in any other drug or medical device clinical trials in 1 month before signing informed consent; * Other circumstances judged by researchers that are not suitable for enrollment .