Comparative Study on the Efficacy of OliNano SEAL and Curodont D' Senz in Treatment of Dentin Hypersensitivity

Al-Azhar University70 enrolled

Overview

This study was conducted to evaluate and compare the efficacy of Olinanoseal and Curodont D'Senz in treatment of dentin hypersensitivity.

Materials and Methods:- A total of ninety (90) samples were used in the study, for dentin permeability test (dye penetration test) and Scanning Electron Microscopic examination (SEM) which were randomly divided into two main groups; group A1, completely removed smear layer, group A2, partially removed smear layer. Each group was subdivided into three subgroups according to the desensitizing agent applied: OliNano SEAL, Curodont D'Senz and the control group that were left untreated. Seventy (70) hypersensitive teeth in ten patients were enrolled for the current study. The subjective assessment of dentin hypersensitivity was done prior to the application of the desensitizing agent (baseline) then immediately, 2 weeks, 4 weeks and 3 months after application of the tested materials. Patients were informed to rate their perception to tactile, air and cold stimuli by using Verbal Rating Score (VRS) and Visual Analogue Scale (VAS).

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Dentin Hypersensitivity

Interventions

OlinanosealDRUG

it contains nanometer particles of fluoroapatite and calcium fluoride - guarantees the resistance to cracks and abrasion. At the same time insoluble nano-fluoroapatites fill all enamel microcracks and closes open dentinal tubules.

Curodont D'senzDRUG

This agent contains p 11-4 peptide in addition to fluoride

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Presence of a minimum of four hypersensitive teeth in each patient. 2. Patients with teeth recorded a discomfort score of two or more to tactile, cold and air stimulation. 3. Teeth having hypersensitivity only on the facial aspect. 4. Patients' willingness to participate in the study Exclusion Criteria: 1. Patients with any medical or dental condition that could impact the study results during its expected length. 2. Patients with a history of drug addictions and use of potent analgesic and/ or anti-inflammatory drugs. 3. Patients who refused to give their consents. 4. Patients with any extensive or unsatisfactory restorations, prosthesis or orthodontic appliances which involve the cervical areas

Locations (1)

Faculty of dental Medicine for girls, Al-AZhar University

Cairo, Egypt

Outcomes

Primary Outcomes

dentin hypersensitivity

pain score (visual analogue scale VAS \["minmum =0 {best}, maximum=10 {worst}\] and verbal rating scale VRS \["minmum =0 {best}, maximum=4 {worst}\])

Time frame: 2 minutes

dentin hypersensitivity

pain score (visual analogue scale VAS \["minmum =0 {best}, maximum=10 {worst}\] and verbal rating scale VRS \["minmum =0 {best}, maximum=4 {worst}\])

Time frame: 2 weeks

dentin hypersensitivity

pain score (visual analogue scale VAS \["minmum =0 {best}, maximum=10 {worst}\]) and verbal rating scale VRS \["minmum =0 {best}, maximum=4 {worst}\])

Time frame: 4 weeks

dentin hypersensitivity

pain score (visual analogue scale VAS \["minmum =0 {best}, maximum=10 {worst}\] and verbal rating scale VRS \["minmum =0 {best}, maximum=4 {worst}\])

Time frame: 3 months

Data from ClinicalTrials.gov

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