Homocysteine in Acute Coronary Syndrome

Sohag University100 enrolled

Overview

This study aims to determine the relation between high homocysteine levels and increased incidence of acute coronary syndrome in young patients

Cross sectional study to: assess homocysteine level in young adult patients presenting with acute coronary syndrome

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Acute Coronary Syndrome

Interventions

Homocysteine levelDIAGNOSTIC_TEST

diagnostic test

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. \- The patients who presented in the hospital with chest pain consistent with acute coronary syndrome with any of the following features: 1. Electrocardiogram (ECG) changes: * ST elevation * ST depression * T wave inversion * recent left bundle branch block 2. Troponin T elevation (Norma value \< 0.06) 2- Age: -Between 18- 40 years (Group A) - Age \> 40 years (Group B) Exclusion Criteria: 1. Chest pain not consistent with acute coronary syndrome 2. Chronic kidney disease (CKD) 3. Rheumatic heart disease (RHD) 4. Congenital heart disease 5. Anemia 6. Cancer

Locations (1)

Sohag University

Sohag, Egypt

Outcomes

Primary Outcomes

Coronary care unit admission with acute coronary syndrome

Acute coronary syndrome hospitalization and cardiovascular deathes and estimated hazard ratios (HR) by use of multivariable Cox regression models

Time frame: From date of randomization up to 1 month

Data from ClinicalTrials.gov

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