Several recent reports have shown an increased prevalence of nonalcoholic fatty liver disease (NAFLD) in those with psoriasis, which may reflect the increased occurrence of metabolic syndrome in this patient population.
the recruitment of 60 fatty live men with chronic disease, psoriasis, will be classified to lifestyle modification group (foe 12 weeks, this patients will take supervised energy or diet restriction program plus their usual immunosuppressive drugs ) and control group will continue their drug program only)
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
for 12 week, the patients of this group will receive their usual immuno-modulating therapy plus life style modification (energy or diet restriction in addition to daily walking, 15000 steps)
the patients will receive the usual immuno-modulating therapy with continued usual diet and activities
Faculty of Physical Therapy Cairo University
Giza, Dokki, Egypt
RECRUITINGPsoriasis Area and Severity Index
it is an index used to measure level and severity of psoriasis
Time frame: It will be measured after 12 weeks
Dermatology Life Quality Index
it is a questinnaire used to assess life quality in psoriasis humans
Time frame: It will be measured after 12 weeks
triglycerides
will measured in plasma
Time frame: It will be measured after 12 weeks
AST
it is plasma aspartate transaminase
Time frame: It will be measured after 12 weeks
ALT
it is plasma Alanine transaminase
Time frame: It will be measured after 12 weeks
BMI
it is body mass index
Time frame: It will be measured after 12 weeks
waist circumference
it will be measured at the level of umbilicus
Time frame: It will be measured after 12 weeks
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