Follow-up Evaluating Clinical and Radiological Outcomes of Total Shoulder Arthroplasty With Permedica's MIRAI Prosthesis

Inclusion Criteria: * both genders * at least 18 years old of age * undergoing a primary total shoulder arthroplasty with MIRAI® Prosthesis System (anatomic or reverse, stemless or stemmed). * Signed informed consent Exclusion Criteria: * Patients requiring a revision shoulder arthroplasty * Persistent chronic or acute infections and all septic conditions * Persistent osteomyelitis local or systemic * Allergy or hypersensitivity to the substances contained in the materials of the implanted components * Acute or chronic neurological and/or musculoskeletal impairment which compromises the shoulder joint function such as an axillary nerve injury affecting the deltoid muscle * Inadequate bone structure which cannot guarantee stability to the prosthetic components * Several vascular, nerve or muscular disorders, which compromise related extremities * Marked osteoporosis, osteomalacia * Hypotrophy of the periarticular soft tissues * Dysmetabolic diseases such as, for example, kidney failure or systemic diseases * Muscular insufficiency * Active neoplastic or metastatic diseases * Any other clinical or physical condition that can invalidate the surgery, the rehabilitation or the prosthesis stability * Patient unwilling or unable to undergo the rehabilitation or to return to follow-up visits * Women in pregnancy, childbearing potential or breastfeeding * Involvement in other ongoing studies or clinical trial.