In left-sided colon and rectal cancer, the occurrence of synchronous para-aortic lymph node metastasis is rare, with the incidence of being approximate 1-2%. Currently, there has been no standard treatment strategy for this situation. The present trial is designed to evaluate the safety and efficacy of para-aortic lymph node dissection for left-sided colon and rectal cancer with synchronous para-aortic lymph node metastasis
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
40
sufficient resection margins of the tumor, D3 dissection of the regional lymph nodes and para-aortic lymph node dissection from the bifurcation of iliac artery to the left renal vein via laparoscopic approach
surgery includes sufficient resection margins of the tumor and D3 dissection of the regional lymph nodes without PALND
Qilu Hospital of Shandong University
Jinan, Shandong, China
5-year OS
5-year overall survival
Time frame: From date of recruitment until the date of death from any cause, assessed up to 5 years
DFS
5-year disease-free survival
Time frame: From date of recruitment until the date of disease recurrece, assessed up to 5 years
LFFS
Local failure free survival
Time frame: From date of recruitment until the date of para-aortic lymph node recurrence, assessed up to 3 years
Postoperative complications
Postoperative complications
Time frame: From date of surgery until the date of 30 days after surgery
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