The purpose of this study is to investigate the therapeutic benefits of flavonoids nutritional supplements quercetin and curcumin for early mild symptoms of COVID-19.
Flavonoids nutritional supplements quercetin and curcumin have demonstrated strong antioxidant, broad-spectrum anti-viral and anti-inflammatory properties including against the respiratory tract infections. They are widely used to boost the immunity against infections and keeping healthy life-style. Results from recent published studies have shown positive results for quercetin and curcumin in patients with COVID-19. In the present study the investigators aim to study the combined beneficial effects of quercetin and curcumin in addition to standard of care for managing early mild symptoms of COVID-19 in community-based patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
50
Standard of care treatment as per the hospital guidelines
Combination of quercetin and curcumin as add-on to the standard of care
King Edward Medical University Teaching Hospital
Lahore, Punjab Province, Pakistan
Testing negative for SARS-CoV-2 by Reverse Transcription Polymerase Chain Reaction (RT-PCR)
Testing of naso-pharyngeal swab for COVID-19
Time frame: Day 7
COVID-19 symptoms improvement
Improvement of the typical symptoms associated with COVID-19 infection
Time frame: Day 7
Improvement in CRP level
Improvement in the CRP levels
Time frame: Day 7
Improvement in D-dimers level
Improvement in D-dimers level
Time frame: Day 7
Improvement in LDH levels
Improvement in LDH levels
Time frame: Day 7
Improvement in ferritin levels
Improvement in Ferritin levels
Time frame: Day 7
Improvement in full blood count (CBC)
Improvement in CBC levels
Time frame: Day 7
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