68Ga-PSMA PET/CT Imaging in Assessment of Prostate Cancer

RenJi Hospital66 enrolled

Overview

Dual-time point 68Ga-PSMA PET/CT could increase the lesion detection in PCa patients, it remains difficult to perform in clinical practice. The possibility of one-time point 68Ga-PSMA PET/CT imaging could be achieved using a total-body PET/CT.

Study Type

OBSERVATIONAL

Enrollment

Conditions

PET/CT Prostate Specific Membrane Antigen IMAGE

Interventions

total-body PET/CTDEVICE

PCa patients who underwent PSMA PET/CT in our clinical center received two-time points scans at 1 h p.i. and 3 h p.i. on a total-body PET/CT scanner.

Eligibility

Sex: MALE

Medical Language ↔ Plain English

Inclusion Criteria: * primary staging of pathology-confirmed PCa or evidence of BCR with PSA value \> 0.2 ng/ml * positive 68Ga-PSMA findings * both standard and delayed scans were performed on the total-body PET/CT Exclusion Criteria: * only one scan was performed * negative PSMA results

Locations (1)

Shanghai jiaotong University School of Medicine, Renji Hospital

Shanghai, Shanghai Municipality, China

Outcomes

Primary Outcomes

Only one-time point scan is possible for PSMA PET/CT

By the use of total- body PET/CT scanner, the imaging quality between the 1 h p.i. and 3 h p.i. imaging acquisition are compared. And the different lesion detection rates at 3 h p.i. and 1 h p.i. are also discussed. The uptake value differences of all lesions are compared.

Time frame: 8 months

Data from ClinicalTrials.gov

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