The investigators designed a study to assess whether there is any change in gut microbiota and postoperative sleep before and after heart valve surgery with cardiopulmonary bypass.
The investigators designed a study to assess whether there is any change in gut microbiota and postoperative sleep before and after heart valve surgery with cardiopulmonary bypass. Firstly, this study aims to characterize the gut microbiota in patients with valve disease treated with surgery. Secondly, it aims to evaluate microbiota and its influence on postoperative sleep.
Study Type
OBSERVATIONAL
Enrollment
36
Duration of sleep was collected with polysomnography on second postoperative night. (from 20:00pm to 06:00am).
the First Hospital of China Medical University
Shenyang, Liaoning, China
gut microbiota
This study will characterize the gut microbiota in one group of 36 patients before and after heart valve surgery
Time frame: from baseline to postoperative 72 hours
postoperative sleep
This study will characterize the postoperative sleep measured by polysomnography in one group of 36 patients after heart valve surgery
Time frame: on the second postoperative night from 20:00 to 6:00
serum metabolites
This study will characterize the serum metabolites in one group of 36 patients before and after heart valve surgery
Time frame: from baseline to postoperative 72 hours
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