A Clinical Study of BRCA and DNA Damage Repair Genes in Blood Samples of Chinese Pancreatic Cancer Patients

RenJi Hospital1,000 enrolled

Overview

This study aims to know the status of BRCA and DDR genes in PDAC patients in China. Peripheral venous blood samples of the patients will be collected for next-generation sequencing of BRCA and DNA damage repair related genes. At the same time, it is necessary to record clinical information such as age, gender, tumor pathological type, tumor stage and grade, whether surgery is performed, the size of postoperative residual lesions, and treatment methods. Prognostic indicators include the association of factors such as PFS, ORR, and DCR are also recorded.

Study Type

OBSERVATIONAL

Enrollment

1,000

Conditions

Pancreatic Cancer

Interventions

ObservationOTHER

This study is an observe research

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients diagnosed with pancreatic cancer * PS score ≤ 2 * no severe heart, cerebrovascular disease, severe coagulation dysfunction or severe mental disorder Exclusion Criteria: * PS score \> 2 * with severe heart, cerebrovascular disease, severe coagulation dysfunction or severe mental disorder

Locations (1)

RenJiH

Shanghai, Shanghai Municipality, China

RECRUITING

Outcomes

Primary Outcomes

Overall survival

Time frame: 2years

Data from ClinicalTrials.gov

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