A retrospective, observational study consisting of patients who presents with typical/atypical chest pain and have an ensuing negative ischemic evaluation
Multicenter, retrospective, observational study consisting of patients who presents with typical/atypical chest pain to the emergency department and have an ensuing negative ischemic evaluation. Planned to review the subsequent diagnostic process in these patients, including patients with CMRI (Cardiac Magnetic Resonance Imaging), PET (Positron Emission Tomography) imaging for evaluation of myocarditis with the goal of quantifying the number of patients who go on to have a proven diagnosis of myocarditis that can explain their presenting symptoms.
Study Type
OBSERVATIONAL
Enrollment
382
To better understand the prevalance of further imaging for evaluation of myocarditis, all patients with negative workup will be included and see what number of patients undergo further CMRI, FGD-PET, or speckle tracking echocardiography. Patients will then be categorized as those with myocarditis with positive diagnosis, negative diagnosis or unknown.
Loma Linda University International Heart Institute
Loma Linda, California, United States
Kansas City Heart Rhythm Institute
Overland Park, Kansas, United States
Montefiore Medical Center
The Bronx, New York, United States
Texas Cardiac Arrhythmia Institute at St. David's Medical Center
Austin, Texas, United States
Number of patients with unrecognized and underlying myocarditis
To quantify the number of patients with unrecognized and underlying myocarditis as a presentation of typical and atypical chest pain followed by a negative ischemic workup.
Time frame: 1/2014 - 1/2022
Association of baseline characteristics or comorbidities with myocarditis
Identification of underlying baseline characteristics or comorbidities that have a greater association with myocarditis presenting as typical/atypical chest pain
Time frame: 1/2014 - 1/2022
Morbidity/mortality
Assessment morbidity/mortality in this population
Time frame: 1/2014 - 1/2022
Diagnostic timing for imaging modalities
Identification of most appropriate diagnostic timing for imaging modalities such as CMRI, FDG PET, speckle tracking echocardiography to diagnose myocarditis after initial negative ischemic workup
Time frame: 1/2014 - 1/2022
Comparison of specific imaging modalities
Comparison of specific imaging modalities (CMRI vs FDG-PET vs speckle tracking echocardiography) and their diagnostic accuracy for myocarditis
Time frame: 1/2014 - 1/2022
Imaging parameters that provide best diagnostic accuracy
Identification of specific imaging parameters on CMRI or PET imaging (late gadolinium enhancement, global dissynchrony measurements, global longitudinal strain, FDG uptake, etc) provide best diagnostic accuracy
Time frame: 1/2014 - 1/2022
Imaging parameters that provide best outcome prediction for morbidity/mortality
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Identification of specific imaging parameters on CMRI or PET imaging (late gadolinium enhancement, global dissynchrony measurements, global longitudinal strain, FDG uptake, etc) provide best outcome prediction for morbidity/mortality.
Time frame: 1/2014 - 1/2022