Aim of the randomized controlled trial is to investigate the effects of endurance training with different intensities on physical performance, body composition and appetite regulation in people with cystic fibrosis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
70
High Intensity Interval Training
Moderate Intensity Continuous Training
Fachklink Satteldüne der DRV Nord
Nebel / Amrum, Schleswig-Holstein, Germany
Strandklinik St. Peter-Ording
Sankt Peter-Ording, Schleswig-Holstein, Germany
change in Peak Oxygen Uptake
measured with peak Oxygen uptake (VO2) in percent predicted
Time frame: at baseline and after 4 weeks of exercise training program
change in Peak Workload
measured with peak Workload in percent predicted
Time frame: at baseline and after 4 weeks of exercise training program
change body fat mass index
measured with body fat mass index (FMI) in kg / m\*2
Time frame: at baseline and after 4 weeks of exercise training program
change in Body fat free mass index
measured with fat free body mass index (FFMI) in kg / m\*2
Time frame: at baseline and after 4 weeks of exercise training program
change in Forced Expiratory Volume in 1 second
measured with Forced Expiratory Volume in 1 second (FEV1) in percent predicted
Time frame: at baseline and after 4 weeks of exercise training program
change in Health related quality of life
measured with the Cystic Fibrosis Questionnaire Revised (CFQ-R); 9 Quality of life domains: Physical, role/school, vitality, emotion, social, body image, eating, treatment burden, health perceptions: 3 symptom scales: Weight, respiratory, and digestion Scores range from 0 to 100, with higher scores indicating better health.
Time frame: at baseline and six and twelve months after completion of exercise training program
appetite control - subjective feeling of hunger
measured with visual analogue scales. The scale consists of a 10 cm vertical line anchored with "not hungry at all" at the left side and with "extremely hungry" at the right side.
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Time frame: at baseline and after 4 weeks of exercise training program