Evaluation of IL-6 in Synovial Fluid in Obese and Normal Weight Patients Suffering From Gonarthrosis During PTA

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio37 enrolled

Overview

Evaluate the concentration of IL-6 in the synovial fluid of obese patients suffering from gonarthrosis during knee arthroplasty surgery

Study Type

OBSERVATIONAL

Enrollment

Conditions

IL-6 Concentration in the Synovial Fluid of Obese Patients is 100% Higher Than the IL-6 Concentration of the Synovial Fluid in Normal Weight Patients

Interventions

Evaluation of IL-6 biomarkers in synovial fluidDIAGNOSTIC_TEST

Evaluation of IL-6 biomarkers in synovial fluid in obese and normal weight patients with gonarthrosis

Eligibility

Sex: ALLMin age: 55 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * age between 55 and 85 years inclusive, * Normal weight patients with BMI 18-24.9 included * Obese patients with BMI ≥ 30 * Patients suffering from gonarthrosis awaiting knee arthroplasty surgery * Patients awaiting knee replacement surgery * Patients who agree to sign informed consent Exclusion Criteria: * Patients under 55 years of age. * Patients over 85 years of age * Patients suffering from diabetes mellitus * Patients who are unable to understand * Patients with severe neurological disorders or severe disability * Rheumatoid arthritis patients * Cancer patients * Patients on immunosuppressive therapy

Locations (1)

IRCCS Istituto Ortopedico Galeazzi

Milan, Italy

Outcomes

Primary Outcomes

Evaluate whether the IL-6 concentration in the synovial fluid of obese patients is 100% higher than the IL-6 concentration of the synovial fluid in normal weight patients

Time frame: 1 day

Data from ClinicalTrials.gov

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