Difficulties understanding speech in noisy environments repeatedly coincide with high-frequency hearing loss. This complaint is commonly exhibited in adults in middle/older age who have a history of noise exposure. In this study, an immersive audiomotor training game will be utilized to drive improvements in speech intelligibility, controlled by an auditory memory training game. Physiological measures will be tracked that could inform clinical assessment of hearing in noise abilities.
Hearing loss is a chronic health disorder affecting approximately 15 percent of Americans. High-frequency hearing loss can be imperceptible when listening in quiet environments. However, in complex noisy environments, individuals can severely suffer from an inability to resolve speech. This is despite having normal audiometric thresholds in the low-frequency range within which speech signals are contained. There are several factors that could contribute to speech intelligibility difficulties that are imperceptible with typical hearing tests. These include impaired temporal encoding at the auditory nerve and the downstream sequelae of peripheral damage in the central auditory pathway. The goal of this study is to assess how a set of physiological measures of auditory/neural processing map onto suprathreshold hearing outcomes. In a previous study, significant improvements in speech intelligibility have resulted from training on an immersive video game. The game uses a closed-loop audiomotor interface design that reinforces sensory-guided feedback. As a control, an auditory memory training game has been developed to replicate user expectations and procedural learning. In this study, an audiomotor game and control game will be used as mechanisms through which to track changes to physiological and perceptual biomarkers in a high frequency hearing loss cohort and a matched normal hearing cohort. Tests will be run pre-training, post- training, and at a follow-up point.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
QUADRUPLE
Closed-loop audiomotor game. Home-based training sessions for 3.5 hours per week over an 8-week.
Auditory memory game. Home-based training sessions for 3.5 hours per week over an 8-week.
Change in Speech Recognition in Noise Performance Accuracy
Keyword recognition accuracy for sentences in noise will be assessed with a clinical test, the QuickSiN. Signal to noise ratios vary from 25 to 0 dB in 5 dB steps.
Time frame: Pre-test / Post-test (8 weeks) / Follow-up (16 weeks)
Change in the neural encoding fidelity for frequency modulated tones
EEG phase coherence to a 500 Hz tone modulated at variable depths at 2Hz.
Time frame: Pre-test / Post-test (8 weeks) / Follow-up (16 weeks)
Change in the psychophysical frequency modulation detection threshold
Frequency modulation detection threshold of 500 Hz carrier modulated at 2Hz.
Time frame: Pre-test / Post-test (8 weeks) / Follow-up (16 weeks)
Increase in pupil dilation while listening to sentences in noise
Growth in pupil dilation over the duration of the sentence will be measured while subjects perform the QuickSiN test at signal to noise ratios varying from 25 to 0 in 5 dB steps.
Time frame: Pre-test / Post-test (8 weeks) / Follow-up (16 weeks)
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