Patients with a definite diagnosis of classical TGN and PIFP will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing. Clinical measures and sensory profiles will be correlated with MRI measures.
Patients with a definite diagnosis of classical TGN and PIFP (according to the 2020 ICOP Classification) will undergo a structured clinical questionnaire and a trigeminal sensory profile using the quantitative sensory testing. Clinical measures and sensory profiles will be correlated with the presence and the geometry of neurovascular compression at MRI. Moreover quantitative structural neuroimaging analysis, such as trigeminal root volume, will be performed in each patient and correlated with clinical and QST data.
Study Type
OBSERVATIONAL
Enrollment
40
Non-invasive assessment of Sensory Profile
The Walton Centre NHS Foundation Trust
Liverpool, United Kingdom
Sensory Profile
Sensory Profile as assessed by Quantitative Sensory Testing
Time frame: Baseline, at the time of visit
Presence of Neurovascular Compression
Presence of Neurovascular Compression defined as absence of any liquor cleft between the trigeminal root and the offending vessel, on dedicated Trigeminal MRI
Time frame: Baseline, at the time of visit
Trigeminal Root Volume
Trigeminal Root Volume as assessed by specific neuroimaging Software (MIPAV)
Time frame: Baseline, at the time of visit
Geometry of Neurovascular Compression
Measurement of the polar coordinates beetween the trigeminal root and the offending vessel as assessed by specific neuroimaging Software (MIPAV)
Time frame: Baseline, at the time of visit
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