Correlation Between Altered Glycometabolic Status and Joint Inflammation in Diabetic Patients With Osteoarthritis Undergoing Knee Arthroplasty

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio40 enrolled

Overview

Evaluate the correlation between altered glycometabolic status and joint inflammation in diabetic patients with osteoarthritis undergoing knee replacement surgery

Study Type

OBSERVATIONAL

Enrollment

Conditions

To Evaluate a Linear Positive Correlation Between Plasma HbA1c and Synovial IL-6 in Diabetic Patients

Interventions

Evaluation of Synovial IL-6 in diabetic patients with gonarthrosisDIAGNOSTIC_TEST

To evaluate if there is a linear positive correlation between plasma glycated hemoglobin concentration HbA1c and synovial IL-6 in diabetic patients

Eligibility

Sex: ALLMin age: 55 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diabetic patients * Patients with osteoarthritis awaiting knee replacement surgery * Patients awaiting knee replacement surgery * Patients who agree to sign informed consent Exclusion Criteria: * Patients less than 55 years of age. * Patients over 85 years of age. * Patients who are unable to understand and want. * Patients with severe neurological disorders or with severe disabilities. * Rheumatoid arthritis patients * Cancer patients * Patients suffering from chronic inflammatory bowel syndromes (RCU and Crohn's disease) * Patients on immunosuppressive therapy

Locations (1)

IRCCS Istituto Ortopedico Galeazzi

Milan, Italy

RECRUITING

Outcomes

Primary Outcomes

To evaluate if there is a linear positive correlation between plasma glycated hemoglobin concentration HbA1c and synovial IL-6 in diabetic patient

Time frame: 2 day

Central Contacts

Cesare Donarini

CONTACT

0248785220 cesare.donarini@grupposandonato.it

Data from ClinicalTrials.gov

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