Use of 1 Minute Sit to Stand Test for Physical Capacity and Effort Related Desaturation in Amyotrophic Lateral Sclerosis

Istanbul University - Cerrahpasa35 enrolled

Overview

The aim of this study is to investigate the usability of the 1 Minute Sit to Stand Test (1 MSTS) in evaluating physical capacity and effort-related desaturation in individuals with Amyotrophic Lateral Sclerosis (ALS). In this context, patients diagnosed with ALS who meet the inclusion criteria will be included in the study. For the physical capacity assessment of patients with ALS at different ambulatory levels included in this study, a 6 minutes walking test (6 MWT) and a 1 MSTS will be applied. Before and at the end of the test, the severity of dyspnea and leg fatigue of the patients will be determined by the Modified Borg Scale; effort-induced desaturation and heart rate by fingertip pulse oximetry; peripheral muscle strength (for the quadriceps femoris muscle) will be evaluated with a hand held dynamometer. When the studies are examined, it has been determined that the 6 MWT is relatively difficult to tolerate in individuals with ALS, it may be difficult to provide the necessary space and equipment for the test, and a shorter, easy-to-apply, and practical evaluation method that can be used instead of this test in the clinic is needed. As a result of this study, the usability of the 1 MSTS in individuals with ambulatory ALS in evaluating physical capacity and desaturation due to effort will be revealed.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Amyotrophic Lateral Sclerosis

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosed with ALS * 18 years and over * Ambulatory * Volunteer to participate in the study Exclusion Criteria: * Having a comorbidity that may affect the results of the study (orthopedic, cardiopulmonary, orthopedic, psychiatric, etc.) * Not willing to participate in the study

Outcomes

Primary Outcomes

ALS Functional Rating Scale (ALSFRS)

ALSFRS, which is used to evaluate the functional status of individuals with ALS, is a scale consisting of 12 parameters: speech, salivation, swallowing, handwriting, feeding, dressing and self-care, turning and covering in bed, walking, climbing stairs, dyspnea, orthopnea and respiratory failure. And evaluated out of a total of 48 points. Each question is scored between 0 and 4 points. While the functionally normal patient gets four points, the scores decrease from four depending on the functional deterioration and zero point is given to the worst functional condition. In this study, the functional levels of the participants will be evaluated with this scale.