The Objectives of This Study Are Study the Safety, Reactogenicity and Obtain Preliminary Data on the Immunogenicity of Flu-M Quadro, 4-valent Inactivated Split Influenza Vaccine, in Healthy Volunteers

Inclusion Criteria: * Voluntarily and personally signed form of informed consent for participation in the trial, before any trial procedure is carried out. * Verified diagnosis "healthy", at that the clinical investigator shall confirm the absence of pathology on the part of the main organs and systems, previously conducted standard clinical, laboratory and instrumental studies did not reveal any diseases. * Age between 18 and 60 years old, inclusively. * Ability to attend all planned visits and all scheduled procedures and studies. * Willingness of the volunteers to complete Self-Observation Diaries in between their visits to a clinical center. * Previous vaccination against seasonal influenza at least 9 months prior to inclusion in this trial. * Consent of the volunteers to use effective contraception methods contraception throughout the trial, including the term of observation for possible post-vaccination reactions Exclusion Criteria: * Known hypersensitivity to any of the components of the tested products, as well as to chicken meat or chicken/quail eggs. * Allergic reaction to any previous influenza vaccination. * Adverse reaction of severe degree of manifestation or serious adverse reaction to previous influenza vaccine administration. * Signs of any disease at the time of inclusion in the trial or if less than 4 weeks have expired after recovery. * Any acute respiratory disease less than 3 months before inclusion in the trial. * Guillain-Barré syndrome (acute polyneuropathy) in the medical history. * History of leukemia, tuberculosis, cancer, autoimmune diseases. * Volunteers who received immunoglobulin or blood products within the last three months before the trial. * Long-term use (exceeding 14 days) of immunosuppressants, systemic corticosteroids or immunomodulatory agents within 6 months before the trial * Vaccination with any vaccine within one month before the vaccination. * Acute infectious or non-communicable diseases, acute exacerbation of a chronic diseases within 4 weeks before the screening. * Scheduled use of vaccines not provided by the tested protocol within 30 days (inclusively) after the vaccination. * Pregnant and breastfeeding women. * Positive blood test results for HIV, syphilis, hepatitis B/C. * Participation in another clinical trial within 30 days before the screening visit or in parallel with the current trial. * History of alcohol addiction, drug addiction or abuse of pharmaceutical products. * Inability or inability to meet the requirements of the protocol, inter lia, for physical, mental or social reasons, according to the clinical investigator