Everolimus Trial in Laryngotracheal Stenosis

Inclusion Criteria: * Current diagnosis of laryngotracheal stenosis * Patient age 18 - 80 years old * Eastern Cooperative Oncology Group (ECOG) performance status of 0 - 1 * Serum total bilirubin and Serum Glutamic Pyruvic Transaminase (SGPT)/(ALT) \< 2.0 times the upper limit of normal; * Serum creatinine \< 2.0 mg/dL; * The patient must be able to comprehend and have signed the informed consent. * The patient must have documentation of their date of laryngotracheal stenosis diagnosis and prior medical/surgical history. * Participants must have also had a prior suspension microlaryngoscopy with endoscopic excision of scar and balloon dilation procedure prior to study entry Exclusion Criteria: * Use of corticosteroids (glucocorticoids) within 7 days of everolimus administration (except physiologic dose equivalent) * Infection requiring treatment with antibiotics, antifungal, or antiviral agents within 7 days of registration * Participation in any clinical trial within 21 days of bone marrow collection involving an investigational drug or device * History of malignancy within five years of registration, except adequately treated basal or squamous cell skin cancer * History of an autoimmune disease (e.g., rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus) requiring active systemic treatment. Hypothyroidism without evidence of Grave's disease or Hashimoto's thyroiditis is permitted. * Human T-cell Lymphotropic Virus type 1 (HTLV-1) or type 2 (HTLV-2) * New York Heart Association (NYHA) class II-IV heart failure within the past 6 months * History of organ transplant with use of immunosuppression * Current use of immunosuppression * Contraindication or documented intolerance to everolimus * Women of childbearing potential who are not on highly effective contraception or abstinent for at least 30 days. Highly effective contraception includes at least two forms of concurrent contraception (Condoms, oral contraceptives, intrauterine devices, contraceptive implants). * Women who are pregnant or breastfeeding, or wishing to become pregnant are excluded from this study * Current use of cytochrome P450 3A inducers (such as some anticonvulsants, rifampin, isoniazid, St. John's wort). * Current use of cytochrome P450 3A inhibitors (such as azole antifungals, nondihydropyridine calcium channel blockers, some macrolide antibiotics, grapefruit) can result in significant interactions * Baseline proteinuria as defined by urine dipstick analysis * History of angioedema * Baseline/continued use of drugs known to be associated with angioedema including angiotensin converting enzyme inhibitors * Significant pulmonary disease independent of laryngotracheal stenosis as defined by and forced expiratory volume at one second (FEV1)/forced vital capacity (FVC) \< 10% of the expected value for the patient's age. * Evidence of a COVID-19 infection including anosmia, upper respiratory symptoms or positive test result within the 30 days prior of trial participation. * Patients who are not fully vaccinated for COVID 19 for at least 4 weeks prior to study entry * Immunosuppressive therapy within previous 21 days or expected need for immunosuppressive therapy for the duration of the study * Known immunodeficiency